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KMID : 0357520070300040373
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Journal of Radiological Science and Technology
2007 Volume.30 No. 4 p.373 ~ p.379
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The Difference of Standardized Uptake Value on PET-CT According to Change of CT Parameters
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Shin Gyoo-Seul
Dong Kyung-Rae
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Abstract
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Purpose: There is difference between PET and PET/CT method on their transmission image for attenuation correction. The CT image is used for attenuation correction on PET/CT and the parameters of CT may be affected on PET image. We performed the phantom study to evaluate whether the change of CT parameters(kilovolts peak and milliampere) affect standardized uptake value(SUV) on PET image.
Material and Method : The data spectrum lung phantom containing diluted [18F]fluorodeoxyglucose ([18F]FDG) solution(1.909 mCi for phantom 1, for phantom 2) was used. The CT images of phantom were acquired with varying parameters (80, 100, 120, 140 for kVp, 10, 20, 30, 40, 50, 60, 70, 80, 90, 100 for mA). The PET images were reconstructed with the each CT images and SUVs were compared.
Result: The SUVs of phantom 1 reconstructed with each 80, 100, 120 and 140 kVp showed , , and , respectively. The SUVs of phantom 2 revealed , , and with elevation of voltage. There was no statistically significant difference of SUVs between groups based on various kVp. Also SUVs of phantom 1 and 2 showed no significant change with elevation of milliampere in CT parameter.
Conclusion: The parameters of CT did not significantly affect SUV on PET image in our study. Therefore we can apply various parameters of CT appropriated for clinical conditions without significant change of SUV on PET CT image.
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KEYWORD
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standardized uptake value, PET, CT, kVp, milliampere
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